Effects of Clostridium butyricum on Growth Performance, Intestinal Health, and Disease Resistance of Hybrid Grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂) Fed with Cottonseed Protein Concentrate (CPC) Replacement of Fishmeal.

ABSTRACT: An 8-week feeding trial was conducted to investigate the effects of C. butyricum on the growth performance, microbiota, immunity response, and disease resistance in hybrid grouper fed with cottonseed protein concentrate (CPC) replacement of fishmeal. Six groups of isonitrogenous and isolipid diets were formulated including a positive control group (50% fishmeal, PC), a negative control group (CPC replaced 50% of fishmeal protein, NC), and Clostridium butyricum supplemented with 0.05% (C1, 5 × 10⁸ CFU/kg), 0.2% (C2, 2 × 10⁹ CFU/kg), 0.8% (C3, 8 × 10⁹ CFU/kg), and 3.2% (C4, 3.2 × 10¹⁰ CFU/kg), respectively, to the NC group. The results showed that weight gain rate and specific growth rate were significantly higher in the C4 group than

SUBMITTER: Pan L 

PROVIDER: S-EPMC10250103 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature