Patterns of Metastatic Recurrence of Genetically Confirmed Myxoid Liposarcoma.

ABSTRACT:

Background

Most sarcomas metastasize predominantly to the lungs, and chest x-ray, or computed tomography, is the most commonly used staging investigation. Myxoid liposarcomas (MLSs) are rare tumors with a tendency to metastasize to extrapulmonary loci. The aim of this study was to assess the locations of the first metastases in MLS patients, to guide the design of effective staging and follow-up imaging protocols.

Methods

Patients treated for MLS between 1987 and 2017 were identified in a prospectively maintained register. Histology of the tumors was reassessed. In addition, the presence of one of the pathognomonic gene translocations was confirmed, uniquely for a retrospective series. The surgical and oncological outcomes were reviewed. A comprehensive review of the literat

SUBMITTER: Homsy P 

PROVIDER: S-EPMC10250512 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature