Postpartum depression: aetiology, pathogenesis and the role of nutrients and dietary supplements in prevention and management.

ABSTRACT: Postpartum depression (PPD) is a challenging psychological disorder faced by 10-30% of mothers across the globe. In India, it occurs among 22% of mothers. Its aetiology and pathophysiology aren't fully understood as of today but multiple theories on the interplay of hormones, neurotransmitters, genetics, epigenetics, nutrients, socio-environmental factors, etc. exist. Nutrients are not only essential for the synthesis of neurotransmitters, but they may also indirectly influence genomic pathways that methylate DNA, and there is evidence for molecular associations between nutritional quality and psychological well-being. Increased behavioural disorders have been attributed to macro- and micronutrient deficiencies, and dietary supplementation has been effective in treating several neuropsychi

SUBMITTER: Rupanagunta GP 

PROVIDER: S-EPMC10250836 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature