Resilience by design: How nature, nurture, environment, and microbiome mitigate stress and allostatic load.

ABSTRACT: Resilience to psychological stress is defined as adaption to challenging life experiences and not the absence of adverse life events. Determinants of resilience include personality traits, genetic/epigenetic modifications of genes involved in the stress response, cognitive and behavioral flexibility, secure attachment with a caregiver, social and community support systems, nutrition and exercise, and alignment of circadian rhythm to the natural light/dark cycle. Therefore, resilience is a dynamic and flexible process that continually evolves by the intersection of different domains in human's life; biological, social, and psychological. The objective of this minireview is to summarize the existing knowledge about the multitude factors and molecular alterations that result from resilience t

SUBMITTER: Chbeir S 

PROVIDER: S-EPMC10251360 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature