Association of serum uric acid with anemia in U.S. adults: a cross-sectional study using secondary data.

ABSTRACT:

Background

High serum uric acid (SUA) is a risk factor of cardiovascular disease (CVD). Abnormal SUA have been correlated with a significant increase in mortality. Anemia is an independent predictor of mortality and CVD. To date, no study has investigated the relationship between SUA and anemia. Here, we explored the correlation between SUA and anemia in the American population.

Methods

The cross-sectional study involved 9205 US adults from NHANES (2011-2014). The relationship between SUA and anemia was explored using multivariate linear regression models. Two-piecewise linear regression model, generalized additive models (GAM) and smooth curve fitting were performed to explore the non-linear relationships between SUA and anemia.

Results

We found a U-shaped non-linear

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10251553 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature