EBV antibody and gastric cancer risk: a population-based nested case-control study in southern China.

ABSTRACT:

Background

We aim to clarify the controversial associations between EBV-related antibodies and gastric cancer risk.

Methods

We analysed the associations between serological Epstein-Barr nuclear antigen 1 immunoglobulin A (EBNA1-IgA) and viral capsid antigen immunoglobulin A (VCA-IgA) by enzyme-linked immunosorbent assay and the risk of gastric cancer in a nested case-control study originated from a population-based nasopharyngeal carcinoma (NPC) screening cohort in Zhongshan, a city of southern China, including 18 gastric cancer cases and 444 controls. Conditional logistic regression was used to calculate the odds ratios (ORs) and corresponding 95% confidence intervals (CIs).

Results

All the sera of cases were sampled before diagnosis and the median time interval was

SUBMITTER: Du Y 

PROVIDER: S-EPMC10251656 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature