Systematic review and meta-analysis of calculating degree of comorbidity of irritable bowel syndrome with migraine.

ABSTRACT:

Background

Irritable bowel syndrome (IBS) and migraines are often comorbid each other. These disorders are likely to be bidirectionally linked through the gut-brain axis and share several underlying mechanisms including central nervous system sensitization. However, quantitative analysis of comorbidity was not reported enough. The aim of this systematic review and meta-analysis was to calculate the present degree of comorbidity of these two disorders.

Methods

A literature search was performed searching for articles describing IBS or migraine patients with the same inverse comorbidity. Pooled odds ratios (ORs) or hazard ratios (HRs) with 95% confidence intervals (CIs) were then extracted. The total effect estimates were determined and presented by random effect forest plots f

SUBMITTER: Todor TS 

PROVIDER: S-EPMC10251688 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature