Protein length distribution is remarkably uniform across the tree of life.

ABSTRACT:

Background

In every living species, the function of a protein depends on its organization of structural domains, and the length of a protein is a direct reflection of this. Because every species evolved under different evolutionary pressures, the protein length distribution, much like other genomic features, is expected to vary across species but has so far been scarcely studied.

Results

Here we evaluate this diversity by comparing protein length distribution across 2326 species (1688 bacteria, 153 archaea, and 485 eukaryotes). We find that proteins tend to be on average slightly longer in eukaryotes than in bacteria or archaea, but that the variation of length distribution across species is low, especially compared to the variation of other genomic features (genome size, nu

SUBMITTER: Nevers Y 

PROVIDER: S-EPMC10251718 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature