Incidence of Atherosclerotic Cardiovascular Disease in Young Adults at Low Short-Term But High Long-Term Risk.

ABSTRACT:

Background

Young adults may have high long-term atherosclerotic cardiovascular disease (ASCVD) risk despite low short-term risk.

Objectives

In this study, we sought to compare the performance of short-term and long-term ASCVD risk prediction tools in young adults and evaluate ASCVD incidence associated with predicted short-term and long-term risk.

Methods

We included adults aged 18 to 39 years, from 2008 to 2009 in a U.S. integrated health care system, and followed them through 2019. We calculated 10-year and 30-year ASCVD predicted risk and assessed ASCVD incidence.

Results

Among 414,260 young adults, 813 had an incident ASCVD event during a median of 4 years (maximum 11 years). Compared with 10-year predicted risk, 30-year predicted risk improved reclassifica

SUBMITTER: An J 

PROVIDER: S-EPMC10251803 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature