Predictive Role of Serum Thyroglobulin after Surgery and before Radioactive Iodine Therapy in Patients with Thyroid Carcinoma.

ABSTRACT:

Introduction

Thyroidectomy followed by radioactive iodine therapy (RAI) is the treatment of choice for differentiated thyroid carcinoma (DTC). Serum thyroglobulin (Tg) measurement has proved to be useful for predicting persistent and/or recurrent disease during follow-up of DTC patients. In our study, we evaluated the risk of disease recurrence in patients with papillary thyroid carcinoma (PTC), who were treated with thyroidectomy and RAI, by measuring serum Tg at different time-points: at least 40 days after surgery, in euthyroidism with TSH < 1.5 and usually 30 days before RAI (Tg_-30), on the day of RAI (Tg₀), and seven days after RAI (Tg₊₇).

Methods

One hundred and twenty-nine patients with PTC were enrolled in this retrospective study. Al

SUBMITTER: Signore A 

PROVIDER: S-EPMC10251887 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature