Ontology highlight
ABSTRACT:
SUBMITTER: Tsukamoto S
PROVIDER: S-EPMC10252039 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature
Tsukamoto Shuichi S Koma Yu-Ichiro YI Kitamura Yu Y Tanigawa Kohei K Azumi Yuki Y Miyako Shoji S Urakami Satoshi S Hosono Masayoshi M Kodama Takayuki T Nishio Mari M Shigeoka Manabu M Yokozaki Hiroshi H
Cancers 20230530 11
Tumor-associated macrophages (TAMs) contribute to disease progression in various cancers, including esophageal squamous cell carcinoma (ESCC). We have previously used an indirect co-culture system between ESCC cell lines and macrophages to analyze their interactions. Recently, we established a direct co-culture system to closely simulate actual ESCC cell-TAM contact. We found that matrix metalloproteinase 9 (MMP9) was induced in ESCC cells by direct co-culture with TAMs, not by indirect co-cultu ...[more]