Stress Adaptation Responses of a Listeria monocytogenes 1/2a Strain via Proteome Profiling.

ABSTRACT: Listeria monocytogenes is a foodborne pathogen that is ubiquitous and largely distributed in food manufacturing environments. It is responsible for listeriosis, a disease that can lead to significant morbidity and fatality in immunocompromised patients, pregnant women, and newborns. Few reports have been published about proteome adaptation when L. monocytogenes is cultivated in stress conditions. In this study, we applied one-dimensional electrophoresis and 2D-PAGE combined with tandem mass spectrometry to evaluate proteome profiling in the following conditions: mild acid, low temperature, and high NaCl concentration. The total proteome was analyzed, also considering the case of normal growth-supporting conditions. A total of 1,160 proteins were identified and those re

SUBMITTER: D'Onofrio F 

PROVIDER: S-EPMC10252599 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature