Comparative Analysis of Hematological and Immunological Parameters in Patients with Primary Sjogren's Syndrome and Peripheral Neuropathy.

ABSTRACT:

Background

Primary Sjögren syndrome (pSS) is a multisystem disorder of autoimmune etiology, frequently involving peripheral nerves. Early detection of peripheral neuropathy (PN) manifestations might improve prognosis and disease control. The purpose of the study was to evaluate the predictive potential of hematological and immunological parameters associated with PN development in pSS patients.

Methods

This single-center retrospective study included patients with pSS who were divided into two groups, according to the occurrence of neurological manifestations throughout the follow-up period.

Results

From the total of 121 pSS patients included in the study, 31 (25.61%) developed neurological manifestations (PN+ group) during the follow-up period. At the moment of pSS di

SUBMITTER: Mihai A 

PROVIDER: S-EPMC10254055 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature