Off-pump injectable versus on-pump conventional tissue valves for pulmonary valve replacement: the injectable valve implantation randomised trial (INVITE).

ABSTRACT:

Objectives

To assess the effectiveness of injectable tissue pulmonary valve compared with standard pulmonary valve in patients requiring pulmonary valve replacement surgery.

Design

A multicentre, single-blind, parallel two-group randomised controlled trial. Participants were blind to their allocation. Follow-up continued for 6 months. Randomised allocations were generated by a computer using block randomisation, stratified by centre.

Setting

Two National Health Service secondary care centres in the UK.

Participants

People aged 12-80 years requiring pulmonary valve replacement.

Interventions

Participants were randomly allocated (1:1 ratio) to injectable pulmonary valve replacement (IPVR) without cardiopulmonary bypass (CPB) or standard pulmonary valve rep

SUBMITTER: Heys R 

PROVIDER: S-EPMC10254783 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature