Ontology highlight
ABSTRACT:
SUBMITTER: Liew LP
PROVIDER: S-EPMC10254852 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature
Liew Lydia P LP Shome Avik A Wong Way W WW Hong Cho R CR Hicks Kevin O KO Jamieson Stephen M F SMF Hay Michael P MP
Molecules (Basel, Switzerland) 20230531 11
The role of hypoxic tumour cells in resistance to radiotherapy, and in suppression of immune response, continues to endorse tumour hypoxia as a bona fide, yet largely untapped, drug target. Radiotherapy innovations such as stereotactic body radiotherapy herald new opportunities for classical oxygen-mimetic radiosensitisers. Only nimorazole is used clinically as a radiosensitiser, and there is a dearth of new radiosensitisers in development. In this report, we augment previous work to present new ...[more]