Calcium Carbonate Coating of 3D-Printed PLA Scaffolds Intended for Biomedical Applications.

ABSTRACT: The incorporation of ceramic additives is the most commonly used strategy to improve the biofunctionality of polymer-based scaffolds intended for bone regeneration. By embedding ceramic particles as a coating, the functionality improvement in the polymeric scaffolds can be concentrated on the cell-surface interface, thus creating a more favourable environment for the adhesion and proliferation of osteoblastic cells. In this work, a pressure-assisted and heat-induced method to coat polylactic acid (PLA) scaffolds with calcium carbonate (CaCO₃) particles is presented for the first time. The coated scaffolds were evaluated by optical microscopy observations, a scanning electron microscopy analysis, water contact angle measurements, compression testing, and an enzymatic degradation

SUBMITTER: Donate R 

PROVIDER: S-EPMC10255753 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature