Static Respiratory System Compliance as a Predictor of Extubation Failure in Patients with Acute Respiratory Failure.

ABSTRACT:

Purpose

Ventilator weaning protocols rely in part on objective indices to best predict extubation failure in the critically ill. We investigated static respiratory system compliance (RC) as a predictor of extubation failure, in comparison to extubation readiness using rapid shallow breathing index (RSBI).

Material and methods

This was a cross-sectional, multi-institutional study of mechanically ventilated patients admitted between 12/01/2017 and 12/01/2019. All patients older than 18 years with a documented spontaneous breathing trial and extubation trial were included. RC and RSBI were calculated prior to the extubation trial. The primary outcome was extubation failure-defined as need for reintubation within 72 h from time of extubation.

Results

Of the 2263 patients,

SUBMITTER: Abplanalp LA 

PROVIDER: S-EPMC10257168 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature