SARS-CoV-2 infection reduces quality of sperm parameters: prospective one year follow-up study in 93 patients.

ABSTRACT:

Background

Short- and long-term implications of SARS-CoV-2 on the quality of the sperm and the results of this on fertility remain largely unknown due to lack of longitudinal studies. In this longitudinal observational cohort study, we aimed to analyse the differential effect and the impact of SARS-CoV-2 infection on different semen quality parameters.

Methods

Sperm quality was assessed using the World Health Organization criteria, DNA damage to sperm cells by quantifying the DNA fragmentation index (DFI) and the high-density stainability (HDS), IgA- and IgG-anti-sperm antibodies (ASA) were assessed with light microscopy.

Findings

SARS-CoV-2 infection was associated with sperm parameters that were independent of spermatogenic cycle like progressive motility, morpholog

SUBMITTER: Depuydt C 

PROVIDER: S-EPMC10257361 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature