Serological and genetic diversity of hepatitis E virus among rabbits population in Egypt.

ABSTRACT:

Background

Hepatitis E virus (HEV) infection has a worldwide distribution and represents an important cause of acute hepatitis. Data on rabbit HEV prevalence and genetic diversity in hyperendemic regions (Egypt) are limited, per the information on rabbit HEV's implications for human pathology.

Aim

This study aimed to determine the prevalence of HEV infection in farmed rabbits from hyperendemic (Egypt) regions, as well as to examine the genetic relatedness of rabbit strains to human strains isolated in these regions.

Methods

Anti-HEV was tested by ELISA from 164 serum samples isolated from rabbits in Egypt. HEV RNA was tested using reverse transcription of a nested polymerase chain reaction with degenerative primers to open reading frames 2 in feces samples from 355 fa

SUBMITTER: El-Adly AM 

PROVIDER: S-EPMC10257457 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature