Transcriptom and miRNA data of PUFA-enriched stimulated murine macrophage and human endothelial cell lines.

ABSTRACT: Inflammation is associated with the adaptation of macrophages and endothelial cells, and the dysregulation of these differentiation processes has been directly linked to both acute and chronic disease states. As cells in constant contact with blood, macrophages and endothelial cells are also under the direct influence of immunomodulatory dietary components such as polyunsaturated fatty acids (PUFA). RNA sequencing analyses allow us to understand the global changes in gene expression occurring during cell differentiation, including both transcriptional (transcriptome) and post-transcriptional (miRNAs) levels. We generated a comprehensive RNA sequencing dataset of parallel transcriptome and miRNA profiles of PUFA-enriched and pro-inflammatory stimulated macrophages and endothelial cells aimi

SUBMITTER: Roessler C 

PROVIDER: S-EPMC10257660 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature