Genomic signatures of local adaptation in recent invasive Aedes aegypti populations in California.

ABSTRACT:

Background

Rapid adaptation to new environments can facilitate species invasions and range expansions. Understanding the mechanisms of adaptation used by invasive disease vectors in new regions has key implications for mitigating the prevalence and spread of vector-borne disease, although they remain relatively unexplored.

Results

Here, we integrate whole-genome sequencing data from 96 Aedes aegypti mosquitoes collected from various sites in southern and central California with 25 annual topo-climate variables to investigate genome-wide signals of local adaptation among populations. Patterns of population structure, as inferred using principal components and admixture analysis, were consistent with three genetic clusters. Using various landscape genomics approaches, which al

SUBMITTER: Soudi S 

PROVIDER: S-EPMC10257851 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature