Comparison of novel ventricular pacing strategies using an electro-mechanical simulation platform.

ABSTRACT:

Aims

Focus of pacemaker therapy is shifting from right ventricular (RV) apex pacing (RVAP) and biventricular pacing (BiVP) to conduction system pacing. Direct comparison between the different pacing modalities and their consequences to cardiac pump function is difficult, due to the practical implications and confounding variables. Computational modelling and simulation provide the opportunity to compare electrical, mechanical, and haemodynamic consequences in the same virtual heart.

Methods and results

Using the same single cardiac geometry, electrical activation maps following the different pacing strategies were calculated using an Eikonal model on a three-dimensional geometry, which were then used as input for a lumped mechanical and haemodynamic model (CircAdapt). We the

SUBMITTER: Meiburg R 

PROVIDER: S-EPMC10259067 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature