Lifetime management of patients with symptomatic severe aortic stenosis: a computed tomography simulation study.

ABSTRACT:

Background

Given enough time, transcatheter heart valves (THVs) will degenerate and may require reintervention. Redo transcatheter aortic valve implantation (TAVI) is an attractive strategy but carries a risk of coronary obstruction.

Aims

We sought to predict how many TAVIs patients could undergo in their lifetime using computed tomography (CT) simulation.

Methods

We analysed paired CT scans (baseline and 30 days post-TAVI) from patients in the LRT trial and EPROMPT registry. We implanted virtual THVs on baseline CTs, comparing predicted valve-to-coronary (VTC) distances to 30-day CT VTC distances to evaluate the accuracy of CT simulation. We then simulated implantation of a second virtual THV within the first to estimate the risk of coronary obstruction due to sinus

SUBMITTER: Medranda GA 

PROVIDER: S-EPMC10259244 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature