Matching enrolled trial participants to disease demographics: Using IRB submissions to identify opportunities for researcher training.

ABSTRACT:

Background

Many diseases are highly prevalent in older adults, yet older adults are often underrepresented in corresponding trials. Our objectives were to (1) determine alignment between Institutional Review Board (IRB) protocol age ranges and enrollment demographics to disease demographics pre- and post-implementation of the 2019 National Institutes of Health (NIH) Lifespan Policy and (2) raise awareness about inclusive recruitment to principal investigators (PIs).

Methods

This was a pre-post study. We reviewed investigator-initiated studies meeting eligibility criteria at Oregon Health & Science University from 2017 to 2018 to determine baseline alignment. Alignment was defined by the level of matching between protocol/enrollment age and disease demographics: 2 points for

SUBMITTER: Eckstrom E 

PROVIDER: S-EPMC10260342 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature