Trigeminocervical pain sensitivity during the migraine cycle depends on headache frequency.

ABSTRACT:

Objective

This experimental study aimed to assess pain sensitivity in low-frequency episodic migraine (LFEM), high-frequency episodic migraine (HFEM), and chronic migraine (CM) patients across the different phases of the migraine cycle.

Method

In this observational, experimental study, clinical characteristics (diary and time from the last/next headache attack), and quantitative sensory testing (QST) (wind-up pain ratio (WUR) and pressure pain threshold (PPT) from the trigeminal area and PPT from the cervical spine) was performed. LFEM, HFEM, and CM were assessed in each of the 4 migraine phases (HFEM and LFEM: interictal, preictal, ictal, and postictal; CM: interictal and ictal) and compared vs. each other's (matched for the phase) and controls.

Results

A total of 56

SUBMITTER: Di Antonio S 

PROVIDER: S-EPMC10260380 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature