Is response evaluation criteria in solid tumors (RECIST) effective in patient selection for radical resection after neoadjuvant immunotherapy with advanced NSCLC?

ABSTRACT:

Background

Neoadjuvant immunotherapy combined with chemotherapy has been used to treat locally advanced non-small cell lung cancer (NSCLC). Several systems have been developed for response evaluation. The aim of this study was to evaluate the predictive value of response evaluation criteria in solid tumors (RECIST) and propose modified RECIST (mRECIST).

Methods

Eligible patients received chemotherapy combined with personalized neoadjuvant immunotherapy. Radical resection was subsequently performed for potentially resectable tumors evaluated by RECIST. The resected specimens were evaluated to determine the response to neoadjuvant therapy.

Results

A total of 59 patients received radical resection following neoadjuvant immunotherapy combined with chemotherapy. According

SUBMITTER: Xu Y 

PROVIDER: S-EPMC10260491 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature