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Hantzsch reaction using copper nitrate hydroxide-containing mesoporous silica nanoparticle with C₃N₄ framework as a novel powerful and reusable catalyst.

ABSTRACT: Copper nitrate hydroxide (CNH)-containing mesoporous silica nanoparticle (MSN) with g-C₃N₄ framework (MSN/C₃N₄/CNH) was fabricated via a four-step hydrothermal synthesis method. Functionalized MSN-based C₃N₄ was prepared, decorated with CNH, and identified by different physicochemical techniques such as FT-IR, XRD, SEM, EDX, and STA analyses. Then, MSN/C₃N₄/CNH composite was utilized as a robust catalyst for the fast fabrication of biologically active polyhydroquinoline derivatives with high yields between 88 and 97% via Hantzsch reaction under mild reaction conditions and short reaction time (within 15 min) owing to synergistic influence of Lewis acid and base sites. Moreover, MSN/C₃N₄/CNH can be straightforwardly recovered and used up to six reaction cycles without a conspicuous decrease in efficiency.

SUBMITTER: Rahmati E

PROVIDER: S-EPMC10261010 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Hantzsch reaction using copper nitrate hydroxide-containing mesoporous silica nanoparticle with C3N4 framework as a novel powerful and reusable catalyst.

Rahmati Ensiyeh E Rafiee Zahra Z

Scientific reports 20230612 1

Copper nitrate hydroxide (CNH)-containing mesoporous silica nanoparticle (MSN) with g-C3N4 framework (MSN/C3N4/CNH) was fabricated via a four-step hydrothermal synthesis method. Functionalized MSN-based C3N4 was prepared, decorated with CNH, and identified by different physicochemical techniques such as FT-IR, XRD, SEM, EDX, and STA analyses. Then, MSN/C3N4/CNH composite was utilized as a robust catalyst for ...[more]

PMID: 37308522

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