Compositional and functional variability of the gut microbiome in children with infantile colic.

ABSTRACT: The inconsolable crying of a child for no apparent reason at an early age is a source of excitement and anxiety for parents. Previous studies have reported that crying may be caused by discomfort associated with the occupation of the intestines of the newborn by microbiota and its vital activity. We conducted a prospective observational study in which 62 newborns and their mothers were recruited. The study comprised two groups, each consisting of 15 infants with colic and 21 controls. Colic and control groups were vaginally born and exclusively breastfed. Fecal samples from children were collected over time from day 1 to 12 months. Full metagenomic sequencing of fecal samples from children and their mothers was carried out. It was determined that the trajectory of the development of the in

SUBMITTER: Kozhakhmetov S 

PROVIDER: S-EPMC10261102 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature