Prenatal vitamin D supplementation and infant vitamin D status in Bangladesh.

ABSTRACT:

Objective

To determine the effect of prenatal maternal vitamin D supplementation on infant vitamin D status in a tropical region where vitamin D supplementation is not routine.

Design

A prospective observational follow-up of a randomized trial.

Setting

Maternal-child health facility in Dhaka, Bangladesh (23°N).

Subjects

Infants born to pregnant women (n 160) randomized to receive 875 µg (35 000 IU) cholecalciferol (vitamin D3) per week (VD) or placebo (PL) during the third trimester were followed from birth until 6 months of age (n 115). Infant serum 25-hydroxyvitamin D concentration (25(OH)D) was measured at <1, 2, 4 and 6 months of age.

Results

Mean infant 25(OH)D was higher in the VD v. PL group at <1 month of age (mean (sd): 80 (20) nmol/l v. 22 (18)

SUBMITTER: Perumal N 

PROVIDER: S-EPMC10261491 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature