Sick sinus syndrome concomitant with myopathy associated with anti-mitochondrial antibodies: a case report.

ABSTRACT:

Background

Anti-mitochondrial antibody (AMA)-associated myopathy is known to be concomitant with primary biliary cirrhosis and to cause both skeletal muscle disorders and arrhythmias, myocardium disorders, and respiratory muscle disorders. We report a case of AMA-associated myopathy in which the bradycardia-related symptoms preceded the skeletal muscle symptoms.

Case summary

A 59-year-old woman visited the emergency room in our hospital following a syncopal event. The patient was bradycardiac (45 b.p.m.) with a junctional rhythm resulting from sick sinus syndrome (SSS) and was suffering from heart failure. Blood tests revealed elevated creatine kinase (CK) and hepatic enzymes. She underwent permanent pacemaker implantation. However, it proved difficult to detect the electric

SUBMITTER: Ishiguro M 

PROVIDER: S-EPMC10261722 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature