Effects of coenzyme Q10 supplementation on lipid profiles and liver enzymes of nonalcoholic fatty liver disease (NAFLD) patients: A systematic review and meta‐analysis of randomized controlled trials

ABSTRACT: Abstract As an antioxidant, coenzyme Q 10 (CoQ10) has been proposed as a possible treatment for non‐alcoholic fatty liver disease (NAFLD). In the present meta‐analysis, we aimed to determine the effects of CoQ10 supplementation on lipid profiles and liver enzymes of NAFLD patients. We searched PubMed, Web of Science, Scopus, and Cochrane Library on 21 April 2022 to retrieve randomized controlled trials on NAFLD patients in which CoQ10 was utilized as a treatment. Data were pooled using the random‐effects model and weighted mean difference (WMD) was considered as the summary effect size. The analysis of the six included studies indicated an overall non‐significant decrease in the lipid profiles (total cholesterol (TC), low‐density lipoprotein cholesterol (LDL), high‐density lipoprotein chol

SUBMITTER: Ardekani A 

PROVIDER: S-EPMC10261764 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature