Evaluation of single-delay arterial spin labeling-based spatial coefficient of variation and histogram-based parameters in relation to cerebrovascular reserve in patients with Moyamoya disease.

ABSTRACT:

Introduction

Single-delay Arterial Spin Labeling (ASL)-based spatial coefficient of variation (CoV_CBF) has been suggested as a measure of hemodynamic disturbance in patients with cerebrovascular diseases. However, spatial CoV_CBF and other histogram-based parameters such as skewness and kurtosis and the volume of the arterial transit time artefact (ATA_vol), has not been evaluated in patients with MMD nor against cerebrovascular reserve (CVR). The aim of this study was to assess whether any associations between spatial CoV_CBF, skewness, kurtosis, and ATA_vol are present and to analyze any potential associations with CVR, derived from single-delay ASL in patients with MMD.

Methods

Fifteen MMD patients were included before or

SUBMITTER: Fahlstrom M 

PROVIDER: S-EPMC10261981 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature