Regulation of whole-transcriptome sequencing expression in COPD after personalized precise exercise training: a pilot study.

ABSTRACT:

Background

Chronic obstructive pulmonary disease (COPD) is one of the world's leading causes of death and a major chronic respiratory disease. Aerobic exercise, the cornerstone of pulmonary rehabilitation, improves prognosis of COPD patients; however, few studies have comprehensively examined the changes in RNA transcript levels and the crosstalk between various transcripts in this context. This study identified the expression of RNA transcripts in COPD patients who engaged in aerobic exercise training for 12 weeks, and further constructions of the possible RNAs networks were made.

Methods

Peripheral blood samples for all four COPD patients who benefited from 12 weeks of PR were collected pre- and post-aerobic exercises and evaluated for the expression of mRNA, miRNA, lncRNA

SUBMITTER: Liu P 

PROVIDER: S-EPMC10262399 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature