Predicting acute radiation dermatitis in breast cancer: a prospective cohort study.

ABSTRACT:

Background

Acute radiation dermatitis (ARD) is one of the most common acute adverse reactions in breast cancer patients during and immediately after radiotherapy. As ARD affects patient quality of life, it is important to conduct individualized risk assessments of patients in order to identify those patients most at risk of developing severe ARD.

Methods

The data of breast cancer patients who received radiotherapy were prospectively collected and analyzed. Serum ferritin, high-sensitivity C-reactive protein (hs-CRP) levels, and percentages of lymphocyte subsets were measured before radiotherapy. ARD was graded (0-6 grade), according to the Oncology Nursing Society Skin Toxicity Scale. Univariate and multivariate logistic regression analyses were used and the odds ratio (OR)

SUBMITTER: Xie Y 

PROVIDER: S-EPMC10262502 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature