GammaTile® (GT) as a brachytherapy platform for rapidly growing brain metastasis

ABSTRACT: Abstract

Background

A subset of brain metastasis (BM) shows rapid recurrence post-initial resection or aggressive tumor growth between interval scans. Here we provide a pilot experience in the treatment of these BM with GammaTile® (GT), a collagen tile-embedded Cesium 131 (131Cs) brachytherapy platform.

Methods

We identified ten consecutive patients (2019–2023) with BM that showed either (1) symptomatic recurrence while awaiting post-resection radiosurgery or (2) enlarged by >25% of tumor volume on serial imaging and underwent surgical resection followed by GT placement. Procedural complication, 30-day readmission, local control, and overall survival were assessed.

Results

For this cohort of ten BM patients, 3 patients suffered tumor progression while awaiting ra

SUBMITTER:  

PROVIDER: S-EPMC10263112 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature