Investigating the active chemical constituents and pharmacology of Nanocnide lobata in the treatment of burn and scald injuries.

ABSTRACT:

Objective

To identify the most effective fraction of Nanocnide lobata in the treatment of burn and scald injuries and determine its bioactive constituents.

Methods

Chemical identification methods were used to analyze solutions extracted from Nanocnide lobata using petroleum ether, ethyl acetate, n-butanol using a variety of color reactions. The chemical constituents of the extracts were identified by ultra-performance liquid chromatography (UPLC)-mass spectrometry (MS). A total of 60 female mice were randomly divided into the following 6 groups: the petroleum ether extract-treated group; the ethyl acetate extract-treated group; the n-butanol extract-treated group; the model group; the control group; and the positive drug group. The burn/scald model was established using Stev

SUBMITTER: Zou Y 

PROVIDER: S-EPMC10263327 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature