The Influence of Minor Aortic Branches in Patient-Specific Flow Simulations of Type-B Aortic Dissection.

ABSTRACT: Type-B aortic dissection (TBAD) is a disease in which a tear develops in the intimal layer of the descending aorta forming a true lumen and false lumen (FL). Because disease outcomes are thought to be influenced by haemodynamic quantities such as pressure and wall shear stress (WSS), their analysis via numerical simulations may provide valuable clinical insights. Major aortic branches are routinely included in simulations but minor branches are virtually always neglected, despite being implicated in TBAD progression and the development of complications. As minor branches are estimated to carry about 7-21% of cardiac output, neglecting them may affect simulation accuracy. We present the first simulation of TBAD with all pairs of intercostal, subcostal and lumbar arteries, using 4D-flow MRI

SUBMITTER: Stokes C 

PROVIDER: S-EPMC10264290 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature