Limb-salvage surgery versus extremity amputation for early-stage bone cancer in the extremities: a population-based study.

ABSTRACT:

Background

Many attempts have been made to induce limb salvage as an alternative to amputation for primary bone cancer in the extremities, but efforts to establish its benefits over amputation yielded inconsistent results with regard to outcomes and functional recovery. This study aimed to investigate the prevalence and therapeutic efficiency of limb-salvage tumor resection in patients with primary bone cancer in the extremities, and to compare it with extremity amputation.

Methods

Patients diagnosed with T1-T2/N0/M0 primary bone cancer in the extremities between 2004 and 2019 were retrospectively identified from the Surveillance, Epidemiology, and End Results program database. Cox regression models were used to test for statistical differences between overall survival (OS)

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC10264616 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature