Histological damage characteristics and quantitive analysis of porcine skin with non-insulated microneedle radiofrequency.

ABSTRACT:

Objective

In recent years, the microneedle radiofrequency (MRF) has been widely used for skin rejuvenation, but histological studies on the immediate trauma caused by different parameters of non-insulated RF microneedles METHODS: The skin of three pigs was treated with different needle depths, pulse widths and energy levels of non-insulated microneedle RF. Samples were collected before, immediately, and 2 weeks after treatment. The immediate histological response of each group was assessed and quantified by hematoxylin and eosin staining, Masson staining and Victoria Blue staining.

Results

In the treatment of non-insulated microneedle RF, different energy levels affected mainly the range of thermal damage (p = 0.044), and different needle depths affected mainly the depth of

SUBMITTER: Feng J 

PROVIDER: S-EPMC10264746 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature