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Risk Factors for Multisystem Inflammatory Syndrome in Children: A Case-control Investigation.


ABSTRACT:

Background

In a 2020 pilot case-control study using medical records, we reported that non-Hispanic Black children were more likely to develop multisystem inflammatory syndrome in children (MIS-C) after adjustment for sociodemographic factors and underlying medical conditions. Using structured interviews, we investigated patient, household, and community factors underlying MIS-C likelihood.

Methods

MIS-C case patients hospitalized in 2021 across 14 US pediatric hospitals were matched by age and site to outpatient controls testing positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within 3 months of the admission date. Caregiver interviews queried race/ethnicity, medical history, and household and potential community exposures 1 month before MIS-C hospit

SUBMITTER: Zambrano LD 

PROVIDER: S-EPMC10265536 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature