Hemodynamic effects of intraoperative 30% versus 80% oxygen concentrations: an exploratory analysis.

ABSTRACT:

Background

Supplemental oxygen leads to an increase in peripheral vascular resistance which finally increases systemic blood pressure in healthy subjects and patients with coronary artery disease, heart failure, undergoing heart surgery, and with sepsis. However, it is unknown whether this effect can also be observed in anesthetized patients having surgery. Thus, we evaluated in this exploratory analysis of a randomized controlled trial the effect of 80% versus 30% oxygen on intraoperative blood pressure and heart rate.

Methods

We present data from a previous study including 258 patients, who were randomized to a perioperative inspiratory FiO₂ of 0.8 (128 patients) versus 0.3 (130 patients) for major abdominal surgery. Continuous arterial blood pressure values wer

SUBMITTER: Reiterer C 

PROVIDER: S-EPMC10265637 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature