OCT biomarkers as predictors of visual improvement in diabetic macular edema eyes receiving dexamethasone implants.

ABSTRACT:

Background

Several optical coherence tomography (OCT) biomarkers have been proposed as predictors for functional and anatomical outcomes in Diabetic Macular Edema (DME). This study aims to examine the impact of these OCT features on the visual acuity improvement of patients with DME after long-acting Dexamethasone intravitreal implants (DEX-I) injection. Furthermore, the safety and impact of DEX-I on clinical parameters, including intraocular pressure (IOP) were assessed.

Methods

In this retrospective observational study, we reviewed the medical records of naïve and non-naïve eyes with DME who received at least one DEX-I. The primary endpoint was visual acuity improvement of ≥ 5 ETDRS letters at 1 month and 4 months after treatment. Secondary outcomes were the changes in OCT

SUBMITTER: Visioli G 

PROVIDER: S-EPMC10265769 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature