Predicting neurocognitive function in pediatric brain tumor early survivorship: The neurological predictor scale and the incremental validity of tumor size.

ABSTRACT:

Background

The Neurological Predictor Scale (NPS) quantifies cumulative exposure to conventional treatment-related neurological risks but does not capture potential risks posed by tumors themselves. This study evaluated the predictive validity of the NPS, and the incremental value of tumor location and size, for neurocognitive outcomes in early survivorship following contemporary therapies for pediatric brain tumors.

Procedure

Survivors (N = 69) diagnosed from 2010 to 2016 were administered age-appropriate versions of the Wechsler Intelligence Scales. Hierarchical multiple regressions examined the predictive and incremental validity of NPS score, tumor location, and tumor size.

Results

Participants (51% female) aged 6-20 years (M = 13.22, SD = 4.09) completed neurocog

SUBMITTER: McCurdy MD 

PROVIDER: S-EPMC10265925 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature