Diagnostics and analysis of SARS-CoV-2: current status, recent advances, challenges and perspectives.

ABSTRACT: The disastrous spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has induced severe public healthcare issues and weakened the global economy significantly. Although SARS-CoV-2 infection is not as fatal as the initial outbreak, many infected victims suffer from long COVID. Therefore, rapid and large-scale testing is critical in managing patients and alleviating its transmission. Herein, we review the recent advances in techniques to detect SARS-CoV-2. The sensing principles are detailed together with their application domains and analytical performances. In addition, the advantages and limits of each method are discussed and analyzed. Besides molecular diagnostics and antigen and antibody tests, we also review neutralizing antibodies and emerging SARS-CoV-2 variants. Fu

SUBMITTER: Dong T 

PROVIDER: S-EPMC10266450 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature