No Cancer Occurrences in 10-year Follow-up after Prophylactic Nipple-sparing Mastectomy.

ABSTRACT: Prophylactic nipple-sparing mastectomies (NSM) have become increasingly common, although there is little long-term data on its efficacy in prevention of breast cancer. The objective of this study was to assess the incidence of breast cancer in a cohort of patients undergoing prophylactic NSM with a median follow-up of 10 years.

Methods

Patients receiving prophylactic NSM at a single institution from 2006 to 2019 were included in a retrospective nature. Patient demographics, genetic mutations, operative details, and specimen pathology were recorded, and all postoperative patient visits and documentation were screened for cancer occurrence. Descriptive statics were performed where appropriate.

Results

Two hundred eighty-four prophylactic NSMs were performed on 228 patients with

SUBMITTER: Boyd CJ 

PROVIDER: S-EPMC10266511 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature