Complications of reversible cerebral vasoconstriction syndrome in relation to age.

ABSTRACT:

Introduction

Reversible cerebral vasoconstriction syndrome (RCVS) has a heterogenous clinical and radiological presentation. We investigated whether RCVS complications vary according to age.

Patients and methods

In a pooled French cohort of 345 patients with RCVS, we assessed (1) rates of clinical and radiological complications, and (2) the functional outcome at 3 months according to age as a continuous variable, and in young patients aged ≤ 49 years versus those aged ≥ 50 years. The Commission Nationale Informatique et Liberté and the local ethics committee approved this study (registration number: 202100733).

Results

The risk for any focal deficit and for any brain lesion were independently associated with increasing age (OR 1.4, 95% CI 1.1-1.8; p = 0.014, and OR 1.

SUBMITTER: Lange KS 

PROVIDER: S-EPMC10267248 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature