Predictive value of cell population data with Sysmex XN-series hematology analyzer for culture-proven bacteremia.

ABSTRACT:

Background

Cell population data (CPD) parameters related to neutrophils, such as fluorescent light intensity (NE-SFL) and fluorescent light distribution width index (NE-WY), have emerged as potential biomarkers for sepsis. However, the diagnostic implication in acute bacterial infection remains unclear. This study assessed the diagnostic value of NE-WY and NE-SFL for bacteremia in patients with acute bacterial infections, and those associations with other sepsis biomarkers.

Methods

Patients with acute bacterial infections were enrolled in this prospective observational cohort study. For all patients, a blood sample, with at least two sets of blood cultures, were collected at the onset of infection. Microbiological evaluation included examination of the blood bacterial load u

SUBMITTER: Miyajima Y 

PROVIDER: S-EPMC10267328 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature