Multivariate prediction of long COVID headache in adolescents using gray matter structural MRI features.

ABSTRACT:

Objective

Headache is among the most frequent symptoms after coronavirus disease 2019 (COVID-19), so-called long COVID syndrome. Although distinct brain changes have been reported in patients with long COVID, such reported brain changes have not been used for predictions and interpretations in a multivariate manner. In this study, we applied machine learning to assess whether individual adolescents with long COVID can be accurately distinguished from those with primary headaches.

Methods

Twenty-three adolescents with long COVID headaches with the persistence of headache for at least 3 months and 23 age- and sex-matched adolescents with primary headaches (migraine, new daily persistent headache, and tension-type headache) were enrolled. Multivoxel pattern analysis (MVPA) was

SUBMITTER: Kim M 

PROVIDER: S-EPMC10267340 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature