Recovery of tetrodotoxin from pufferfish viscera extract by amine-functionalized magnetic nanocomposites.

ABSTRACT: Tetrodotoxin (TTX) has been widely used in pharmacology, food poisoning analysis, therapeutic use, and neurobiology. In the last decades, the isolation and purification of TTX from natural sources (e.g., pufferfish) were mostly based on column chromatography. Recently, functional magnetic nanomaterials have been recognized as promising solid phases for the isolation and purification of bioactive compounds from aqueous matrices due to their effective adsorptive properties. Thus far, no studies have been reported on the utilization of magnetic nanomaterials for the purification of TTX from biological matrices. In this work, an effort has been made to synthesize Fe₃O₄@SiO₂ and Fe₃O₄@SiO₂-NH₂ nanocomposites for

SUBMITTER: Tran DT 

PROVIDER: S-EPMC10267608 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature