Pregnancy, Delivery, and Neonatal Outcomes Associated With Maternal Obsessive-Compulsive Disorder: Two Cohort Studies in Sweden and British Columbia, Canada.

ABSTRACT:

Importance

Obsessive-compulsive disorder (OCD) is associated with adverse health-related outcomes. However, pregnancy and neonatal outcomes among women with OCD have been sparsely studied.

Objective

To evaluate associations of maternal OCD with pregnancy, delivery, and neonatal outcomes.

Design, setting, and participants

Two register-based cohort studies in Sweden and British Columbia (BC), Canada, included all singleton births at 22 weeks or more of gestation between January 1, 1999 (Sweden), or April 1, 2000 (BC), and December 31, 2019. Statistical analyses were conducted between August 1, 2022, and February 14, 2023.

Exposure

Maternal OCD diagnosis recorded before childbirth and use of serotonin reuptake inhibitors (SRIs) during pregnancy.

Main outcomes a

SUBMITTER: Fernandez de la Cruz L 

PROVIDER: S-EPMC10267772 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature